Williamson has been nursing a low back bone bruise he suffered in a fall during a game on March 19 while McCollum has been sidelined by a right foot bone bruise from a loss to Detroit on March 23rd.
It marked another season in which injuries contributed to a disappointing season for New Orleans, starting with the broken hand suffered by newly acquired star guard Dejounte Murray in the season-opener.
Murray suffered a torn Achilles tendon later in the season while Williamson missed time with a hamstring strain.
Williamson made a strong return from that injury, finishing the season averaging 24.6 points, 7.2 rebounds and 5.3 assists per game - but he only played 30 games.
The former number one overall draft pick was hoping for better after playing in a career-high 70 games in the 2023-24 season.
But with seven games left in the regular season, the Pelicans are next to last in the Western Conference.