Matias Vargas scored a hat-trick as 10-man Shanghai Port defeated South Korea's Ulsan HD 3-1 while Japan's Kawasaki Frontale won 3-0 over Buriram United and Shandong Taishan claimed a 1-0 win over Johor Darul Ta'zim.
Takayuki Yoshida's Kobe side lead the east Asian standings with 13 points from the first five league phase games as clubs attempt to finish in the top eight places in the 12-team division to advance to the last 16.
Kobe were made to work for their win, seeing a two-goal lead given to them by Ryuho Kikuchi's 40th minute header and an own goal from Storm Roux four minutes after the restart wiped out.
Hotaru Yamauchi's own goal in the 54th minute and a strike from Bailey Brandtman with 16 minutes remaining pulled the A-League champions level.
But in the 81st minute Peraic-Cullen let Daiju Sasaki's shot from the edge of the penalty area slip through his hands to gift Kobe the three points.
Vargas, meanwhile, put Shanghai Port in front in Ulsan when he stumbled through the home side's penalty area before sliding the ball through Jo Su-huk's legs in the 11th minute.
The Argentinian doubled his team's advantage with a low strike 12 minutes later having been found unmarked in the area by Oscar as the former Chelsea man made the most of a misplaced pass by Ko Seung-beom.
The Chinese champions were reduced to 10 men in the 31st minute when Li Ang picked up his second booking for pulling back Lee Chung-yong and Joo Min-kyu reduced the deficit in the 73rd minute.
Vargas, though, restored Shanghai's cushion with seven minutes left when he arrowed a shot from the edge of the area into the top corner on the run as Kevin Muscat's team climbed into eighth place, moving above Buriram on goal-difference.
Late goals from Sota Miura, Daiya Tono and Soma Kanda secured a 3-0 victory for Kawasaki Frontale over hosts Buriram as Toru Oniki's team jumped up to third in the table with nine points.
In Jinan, Zeca's 68th minute goal gave Shandong a 1-0 win over visitors JDT to move the Chinese Super League side onto seven points in seventh place.
Yokohama F Marinos, last season's runners-up, take on Pohang Steelers on Wednesday with South Korea's Gwangju FC, currently in second place, hosting Shanghai Shenhua.
Al Hilal booked their place in the last 16 of the Asian Champions League Elite on Tuesday despite being held to a 1-1 draw by hosts Al-Sadd in Qatar that ended the Saudi club's perfect start to the league phase of the competition.
The draw, coupled with a 3-1 loss for Iraqi side Al Shorta against Al Wasl from the United Arab Emirates, means Cristiano Ronaldo's Al Nassr also progress having defeated Al-Gharafa on Monday.
The pair join compatriots Al-Ahli as early qualifiers for the knockout rounds with the Jeddah-based side topping the standings in west Asia with maximum points after five matches.
The top eight teams in the 12-club league phase in both west and east Asia advance to the last 16, which will be played over two legs on a home-and-away basis in March.
Al-Hilal took a perfect record into their meeting with Al-Sadd at Jassim bin Hamed Stadium and went in front in the 10th minute when Ali Al-Bulahyi pounced at the far post after Mohammed Kanno had flicked on Salem Al-Dawsari's corner.
Aleksandar Mitrovic hit the crossbar in the second half as Al-Hilal sought a second goal but, with 19 minutes remaining, Al-Sadd levelled when Akram Afif's low cross was tapped in by Paulo Otavio.
Tarek Salman then hit the woodwork for the hosts in a frantic finish which saw referee Kim Jong-hyeok turn down a pair of late Al-Hilal penalty claims after consulting the pitch-side monitor.
The draw, however, was enough to secure Al-Hilal's passage to the next round while Al-Sadd also remain on track for the next phase despite dropping to fifth with nine points.
Al-Wasl climbed above the Qataris and into fourth with their win over Al-Shorta, which came after Jonatas Santos had put the UAE club ahead in Karbala in the 14th minute.
Fahd Yousef equalised for Al-Shorta five minutes into the second half but goals from Fabio Lima and Nicolas Gimenez in the 64th and 92nd minutes respectively sealed the win for the visitors.