Ahead of going to Brentford on Saturday, Slot was asked about Arsenal moving within four points of their leadership.
"I didn't even know Arsenal are playing later than us, I look at the opponent for us. If this is going to be the resistance we have every week then this is a harder league than Holland, is what I thought after my first home game," he said.
"They created chances against Man City and their manager has done a great job, they have worked together for a long time. I have no other focus like when Arsenal or Chelsea plays or whoever.
"I don't think we are as much as the media are thinking about the table, we are trying to get the best out of players, the staff and the players. These players know how long this season is and how good they have to be to win something, which is not something that happens every week.
"So we focus on a good session today and a good game tomorrow and the only way to get a result is to work on best possible basis every day."
Asked about captain Virgil van Dijk's quip of Liverpool being in "crisis", Slot also stated: "This season shows the strength of the league, even yesterday was quite a surprise to see Southampton go toe to toe with Manchester United for so long.
"It's harder to win in second half of the season than first, teams are longer together, others bring players in and teams are fighting for Europe, titles, to stay in the league.
"Brentford is an example of a team who were already strong in first half. A very good team for a few years now. They have shown that."
On the workload of his players, Slot admits it is simply the reality of the Premier League.
"If I remember, this has been the situation since we started against Brentford, that was maybe the only week we didn't have a double programme, maybe you say there are international breaks, which is true but no time off for players.
"A break in March but I know a bit better that the Dutch play Spain, so Cody, Ryan, Virgil have a tough game and you say they have a break."
When asked about the form of his strikers, Slot insisted he was happy with what he was seeing from Darwin Nunez.
"It's your perception, not mine that he is struggling for confidence. He was involved in goals against Accrington and Fulham and he scored against Southampton.
"So for me it's the life of a striker, sometimes you score, sometimes you don't and he hasn't started every week.
"We score every game except for Spurs in the Cup, so that tells me we have goals in our team. Darwin will score like he has done already. I don't see him struggling that much as you see it."